Oral stem cells include oral epithelial stem cells and oral mesenchymal stem cells. These cells can be isolated from oral tissues, including teeth and their surrounding or supporting structures. In daily dental clinical practice, there are many oral tissues that are wasted from patients. Each year, there are millions of teeth that are disposed from clinics and hospitals as waste. However, the teeth and their surrounding tissues are not useless because scientists can get stem cells from them. Baby teeth in particular are more important as they can provide high quality stem cells. From the pulp of third molar teeth, scientists can easily obtain oral mesenchymal stem cells. The tissue attached to the surface of wisdom tooth also provides stem cells. These oral stem cells are not only imperative in regenerative dentistry, but also in regenerative medicine as well.
Current research in oral stem cells
Stem cells help in organ formation. In every organism, each tissue appears from pleuripotent embryonic stem cells. These embryonic stem cells differentiate into multipotent stem cells including epithelial, mesenchymal, and other tissue specific stem cells. Interactions among the cells initiate and regulate processes that form highly specialised functional tissues and organs like your tooth, hair follicle, lungs, kidneys and other tubular organs. As the organism matures, the pleuripotent embryonic stem cells are vanished and some multipotent adult stem cells remain in the developed tissue to sustain the other structures and repairing injuries. Adult epithelial and mesenchymal stem cells stay inside oral tissue.
From dental pulp, gums, and periodontal ligament, scientists are able to acquire mesenchymal stem cells. During the past two decades, researchers have found that oral stems have potential for the regeneration of tissues and organs. For example, oral epithelial stem cells have been demonstrated to repair cornea of the eye and lining of food pipe in patients. Oral mesenchymal stem cells have a lot more applications in both regenerative dentistry and regenerative medicine. They have the capacity to give rise to cells that can help in the regeneration of dental pulp, periodontal tissue, neuron, muscle, bone, cartilage, liver, heart, pancreas, and blood vessels.
Stem cell banking
To preserve your or your family member’s stem cells, contact Prosmiles who will guide you regarding stem cell banking. ProSmiles have a dental sampling kit that is designed to ensure the safe transportation of the tooth, in ideal conditions, till such time as it reaches the laboratory. On the day of collection, a dentist will perform this procedure. The collected tooth will be put inside the dental sampling kit with the relevant details written on it. The paramedic will collect the blood sample and place it in the dental sampling kit. This dental sampling kit is then carefully packed by the paramedic and will ensure its courier to the laboratory for future use.
Isolation and characterisation of dental tissue-derived stem cells and address the potential of these cell types for use in regenerative cell transplantation therapy is the future of dentistry.
Contact us today
Would you like to know more about how stem cell plays a part in your dental care? Contact Prosmiles to speak with one of our experienced dentists today.